Anquilosis de cadera por osificación heterotópica: reporte de un caso
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Publicado:
oct 17, 2024
Palabras clave:
Osificación heterotópica, cadera, reemplazo articular de cadera, clasificación de Brooker
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Resumen
Se presenta el caso de un paciente de 59 años con una osificación heterotópica en la cadera derecha. Este trastorno se desarrolló como resultado de una hemiplejia derecha secundaria a un traumatismo craneoencefálico sufrido en un accidente de tránsito. Posteriormente, el paciente sufrió una fractura intracapsular en la cadera izquierda que requirió una cirugía de reemplazo articular. Debido a sus limitaciones, derivadas de su condición neurológica y el reposo posoperatorio, se desarrolló una osificación heterotópica grado IV de Brooker, con anquilosis en la cadera no operada. Esta osificación requirió una resección quirúrgica, se detectó una notoria vascularización y proximidad al paquete neurovascular inguinal. Luego de la cirugía, el paciente recibió radioterapia y antinflamatorios no esteroides. Se observó una notable mejoría en los arcos de movilidad y en la independencia durante el seguimiento de un año, sin evidencia de recurrencias.
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Londoño García, R., Avendaño, V. A., Cano González, M. Ángel, Arboleda, J. P., & Moore Velásquez, J. L. (2024). Anquilosis de cadera por osificación heterotópica: reporte de un caso . Revista De La Asociación Argentina De Ortopedia Y Traumatología, 89(5), 519-527. https://doi.org/10.15417/issn.1852-7434.2024.89.5.1909
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Citas
1. Zurriaga J, Argüelles F, Mifsut D, Silvestre A. Osificación heterotópica de cadera: revisión bibliográfica y
presentación de un caso. Rev Esp Cir Osteoarticular [Internet] 2019;54(227). Disponible en:
https://rodrigo.uv.es/bitstream/handle/10550/71856/7058135.pdf?sequence=1&isAllowed=y
2. Shehab D, Elgazzar AH, Collier BD. Heterotopic ossification. J Nucl Med 2002;43(3):346-53. PMID: 11884494
3. Cunha DA, Camargos S, Passos VMA, Mello CM, Vaz LS, Lima LRS. Heterotopic ossification after stroke: Clinical
profile and severity of ossification. J Stroke Cerebrovasc Dis 2019;28(2):513-20. https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.10.032
4. Bedi A, Zbeda RM, Bueno VF, Downie B, Dolan M, Kelly BT. The incidence of heterotopic ossification after hip
arthroscopy. Am J Sports Med 2012;40(4):854-63. https://doi.org/10.1177/0363546511434285
5. Cipriano CA, Pill SG, Keenan MA. Heterotopic ossification following traumatic brain injury and spinal cord injury. J Am Acad Orthop Surg 2009;17(11):689-97. https://doi.org/10.5435/00124635-200911000-00003
6. Medina A, Shankowsky H, Savaryn B, Shukalak B, Tredget EE. Characterization of heterotopic ossification in burn patients. J Burn Care Res 2014;35(3):251-6. https://doi.org/10.1097/BCR.0b013e3182957768
7. DeBaun MR, Ziino C, LaPrade C, Pun S, Avedian RS, Bellino MJ. An anatomic classification for heterotopic
ossification about the hip. J Orthop 2020;28;21:228-31. https://doi.org/10.1016/j.jor.2020.03.038
8. Hug KT, Alton TB, Gee AO. Classifications in brief: Brooker classification of heterotopic ossification after total hip arthroplasty. Clin Orthop Relat Res 2015;473(6):2154-7. https://doi.org/10.1007/s11999-014-4076-x
9. Wosczyna MN, Biswas AA, Cogswell CA, Goldhamer DJ. Multipotent progenitors resident in the skeletal muscle
interstitium exhibit robust BMP dependent osteogenic activity and mediate heterotopic ossification. J Bone Miner
Res 2012;27(5):1004-17. https://doi.org/10.1002/jbmr.1562
10. Bidner SM, Rubins IM, Desjardins JV, Zukor DJ, Goltzman D. Evidence for a humoral mechanism for enhanced
osteogenesis after head injury. J Bone Joint Surg Am 1990;72(8):1144-9. PMID: 2398084
11. Salisbury E, Rodenberg E, Sonnet C, Hipp J, Gannon FH, Vadakkan TJ, et al. Sensory nerve induced inflammation contributes to heterotopic ossification. J Cell Biochem 2011;112(10):2748-58. https://doi.org/10.1002/jcb.23225
12. Kurer MH, Khoker MA, Dandona P. Human osteoblast stimulation by sera from paraplegic patients with heterotopic ossification. Paraplegia 1992;30(3):165-8. https://doi.org/10.1038/sc.1992.48
13. Cholok D, Chung MT, Ranganathan K, Ucer S, Day D, Davis TA, et al. Heterotopic ossification and the elucidation of pathologic differentiation. Bone 2018;109:12-21. https://doi.org/10.1016/j.bone.2017.09.019
14. Ranganathan K, Loder S, Agarwal S, Wong VW, Forsberg J, Davis TA, et al. Heterotopic ossification: Basic-science principles and clinical correlates. J Bone Joint Surg Am 2015;1;97(13):1101-11. https://doi.org/10.2106/JBJS.N.01056
15. Barbato M, D’Angelo E, Di Loreto G, Menna A, Di Francesco A, Salini V, et al. Adherence to routine use of
pharmacological prophylaxis of heterotopic ossification after total hip arthroplasty: results from an Italian
multicenter, prospective, observational survey. J Orthop Traumatol 2012;13(2):63-7.
https://doi.org/10.1007/s10195-012-0180-4
16. Blackwell KA, Raisz LG, Pilbeam CC. Prostaglandins in bone: bad cop, good cop? Trends Endocrinol Metab 2010; 21(5):294-301. https://doi.org/10.1016/j.tem.2009.12.004
17. Joice M, Vasileiadis GI, Amanatullah DF. Non-steroidal anti-inflammatory drugs for heterotopic ossification
prophylaxis after total hip arthroplasty: a systematic review and meta-analysis. Bone Joint J 2018;100-B(7):915-22.
https://doi.org/10.1302/0301-620X.100B7.BJJ-2017-1467.R1
18. Grohs JG, Schmidt M, Wanivenhaus A. Selective COX-2 inhibitor versus indomethacin for the prevention of
heterotopic ossification after hip replacement: a double-blind randomized trial of 100 patients with 1-year follow-up. Acta Orthop 2007;78(1):95-8. https://doi.org10.1080/17453670610013484
19. Haran M, Bhuta T, Lee B. Pharmacological interventions for treating acute heterotopic ossification. Cochrane
Database Syst Rev 2004;(4):CD003321. https://doi.org/10.1002/14651858.CD003321.pub3
20. Fransen M, Anderson C, Douglas J, MacMahon S, Neal B, Norton R, et al. Safety and efficacy of routine
postoperative ibuprofen for pain and disability related to ectopic bone formation after hip replacement surgery
(HIPAID): randomised controlled trial. BMJ 2006;9;333(7567):519. https://doi.org/10.1136/bmj.38925.471146.4F
21. Popovic M, Agarwal A, Zhang L, Yip C, Kreder HJ, Nousiainen MT, et al. Radiotherapy for the prophylaxis of
heterotopic ossification: a systematic review and meta-analysis of published data. Radiother Oncol 2014;113(1):10-7. https://doi.org/10.1016/j.radonc.2014.08.025
22. Seegenschmiedt MH, Martus P, Goldmann AR, Wölfel R, Keilholz L, Sauer R. Preoperative versus postoperative
radiotherapy for prevention of heterotopic ossification (HO): first results of a randomized trial in high-risk patients. Int J Radiat Oncol Biol Phys 1994;30;30(1):63-73. https://doi.org/10.1016/0360-3016(94)90520-7
23. Ploumis A, Belbasis L, Ntzani E, Tsekeris P, Xenakis T. Radiotherapy for prevention of heterotopic ossification of the elbow: a systematic review of the literature. J Shoulder Elbow Surg 2013;22(11):1580-8. https://doi.org/10.1016/j.jse.2013.07.045
24. Coons D, Godleski M. Range of motion exercises in the setting of burn-associated heterotopic ossification at the elbow: case series and discussion. Burns 2013;39(4):e34-8. https://doi.org/10.1016/j.burns.2012.10.014
25. Pakos EE, Ioannidis JP. Radiotherapy vs. nonsteroidal anti-inflammatory drugs for the prevention of heterotopic ossification after major hip procedures: a meta-analysis of randomized trials. Int J Radiat Oncol Biol Phys 2004;60(3):888-95. https://doi.org/10.1016/j.ijrobp.2003.11.015
presentación de un caso. Rev Esp Cir Osteoarticular [Internet] 2019;54(227). Disponible en:
https://rodrigo.uv.es/bitstream/handle/10550/71856/7058135.pdf?sequence=1&isAllowed=y
2. Shehab D, Elgazzar AH, Collier BD. Heterotopic ossification. J Nucl Med 2002;43(3):346-53. PMID: 11884494
3. Cunha DA, Camargos S, Passos VMA, Mello CM, Vaz LS, Lima LRS. Heterotopic ossification after stroke: Clinical
profile and severity of ossification. J Stroke Cerebrovasc Dis 2019;28(2):513-20. https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.10.032
4. Bedi A, Zbeda RM, Bueno VF, Downie B, Dolan M, Kelly BT. The incidence of heterotopic ossification after hip
arthroscopy. Am J Sports Med 2012;40(4):854-63. https://doi.org/10.1177/0363546511434285
5. Cipriano CA, Pill SG, Keenan MA. Heterotopic ossification following traumatic brain injury and spinal cord injury. J Am Acad Orthop Surg 2009;17(11):689-97. https://doi.org/10.5435/00124635-200911000-00003
6. Medina A, Shankowsky H, Savaryn B, Shukalak B, Tredget EE. Characterization of heterotopic ossification in burn patients. J Burn Care Res 2014;35(3):251-6. https://doi.org/10.1097/BCR.0b013e3182957768
7. DeBaun MR, Ziino C, LaPrade C, Pun S, Avedian RS, Bellino MJ. An anatomic classification for heterotopic
ossification about the hip. J Orthop 2020;28;21:228-31. https://doi.org/10.1016/j.jor.2020.03.038
8. Hug KT, Alton TB, Gee AO. Classifications in brief: Brooker classification of heterotopic ossification after total hip arthroplasty. Clin Orthop Relat Res 2015;473(6):2154-7. https://doi.org/10.1007/s11999-014-4076-x
9. Wosczyna MN, Biswas AA, Cogswell CA, Goldhamer DJ. Multipotent progenitors resident in the skeletal muscle
interstitium exhibit robust BMP dependent osteogenic activity and mediate heterotopic ossification. J Bone Miner
Res 2012;27(5):1004-17. https://doi.org/10.1002/jbmr.1562
10. Bidner SM, Rubins IM, Desjardins JV, Zukor DJ, Goltzman D. Evidence for a humoral mechanism for enhanced
osteogenesis after head injury. J Bone Joint Surg Am 1990;72(8):1144-9. PMID: 2398084
11. Salisbury E, Rodenberg E, Sonnet C, Hipp J, Gannon FH, Vadakkan TJ, et al. Sensory nerve induced inflammation contributes to heterotopic ossification. J Cell Biochem 2011;112(10):2748-58. https://doi.org/10.1002/jcb.23225
12. Kurer MH, Khoker MA, Dandona P. Human osteoblast stimulation by sera from paraplegic patients with heterotopic ossification. Paraplegia 1992;30(3):165-8. https://doi.org/10.1038/sc.1992.48
13. Cholok D, Chung MT, Ranganathan K, Ucer S, Day D, Davis TA, et al. Heterotopic ossification and the elucidation of pathologic differentiation. Bone 2018;109:12-21. https://doi.org/10.1016/j.bone.2017.09.019
14. Ranganathan K, Loder S, Agarwal S, Wong VW, Forsberg J, Davis TA, et al. Heterotopic ossification: Basic-science principles and clinical correlates. J Bone Joint Surg Am 2015;1;97(13):1101-11. https://doi.org/10.2106/JBJS.N.01056
15. Barbato M, D’Angelo E, Di Loreto G, Menna A, Di Francesco A, Salini V, et al. Adherence to routine use of
pharmacological prophylaxis of heterotopic ossification after total hip arthroplasty: results from an Italian
multicenter, prospective, observational survey. J Orthop Traumatol 2012;13(2):63-7.
https://doi.org/10.1007/s10195-012-0180-4
16. Blackwell KA, Raisz LG, Pilbeam CC. Prostaglandins in bone: bad cop, good cop? Trends Endocrinol Metab 2010; 21(5):294-301. https://doi.org/10.1016/j.tem.2009.12.004
17. Joice M, Vasileiadis GI, Amanatullah DF. Non-steroidal anti-inflammatory drugs for heterotopic ossification
prophylaxis after total hip arthroplasty: a systematic review and meta-analysis. Bone Joint J 2018;100-B(7):915-22.
https://doi.org/10.1302/0301-620X.100B7.BJJ-2017-1467.R1
18. Grohs JG, Schmidt M, Wanivenhaus A. Selective COX-2 inhibitor versus indomethacin for the prevention of
heterotopic ossification after hip replacement: a double-blind randomized trial of 100 patients with 1-year follow-up. Acta Orthop 2007;78(1):95-8. https://doi.org10.1080/17453670610013484
19. Haran M, Bhuta T, Lee B. Pharmacological interventions for treating acute heterotopic ossification. Cochrane
Database Syst Rev 2004;(4):CD003321. https://doi.org/10.1002/14651858.CD003321.pub3
20. Fransen M, Anderson C, Douglas J, MacMahon S, Neal B, Norton R, et al. Safety and efficacy of routine
postoperative ibuprofen for pain and disability related to ectopic bone formation after hip replacement surgery
(HIPAID): randomised controlled trial. BMJ 2006;9;333(7567):519. https://doi.org/10.1136/bmj.38925.471146.4F
21. Popovic M, Agarwal A, Zhang L, Yip C, Kreder HJ, Nousiainen MT, et al. Radiotherapy for the prophylaxis of
heterotopic ossification: a systematic review and meta-analysis of published data. Radiother Oncol 2014;113(1):10-7. https://doi.org/10.1016/j.radonc.2014.08.025
22. Seegenschmiedt MH, Martus P, Goldmann AR, Wölfel R, Keilholz L, Sauer R. Preoperative versus postoperative
radiotherapy for prevention of heterotopic ossification (HO): first results of a randomized trial in high-risk patients. Int J Radiat Oncol Biol Phys 1994;30;30(1):63-73. https://doi.org/10.1016/0360-3016(94)90520-7
23. Ploumis A, Belbasis L, Ntzani E, Tsekeris P, Xenakis T. Radiotherapy for prevention of heterotopic ossification of the elbow: a systematic review of the literature. J Shoulder Elbow Surg 2013;22(11):1580-8. https://doi.org/10.1016/j.jse.2013.07.045
24. Coons D, Godleski M. Range of motion exercises in the setting of burn-associated heterotopic ossification at the elbow: case series and discussion. Burns 2013;39(4):e34-8. https://doi.org/10.1016/j.burns.2012.10.014
25. Pakos EE, Ioannidis JP. Radiotherapy vs. nonsteroidal anti-inflammatory drugs for the prevention of heterotopic ossification after major hip procedures: a meta-analysis of randomized trials. Int J Radiat Oncol Biol Phys 2004;60(3):888-95. https://doi.org/10.1016/j.ijrobp.2003.11.015