Outcomes of cryopreserved allograft in long bones fractures and nonunions

  • Ignacio Alejandro Fernández Savoy Sanatorio Allende
  • Leandro Salcedo Zunino Sanatorio Allende
  • Alejandro Malvarez Sanatorio Allende
  • Ignacio Pioli Sanatorio Allende
  • Bartolomé Luis Allende Sanatorio Allende
  • Christian Antonio Allende Sanatorio Allende
Keywords: Bone allograft, Bone defect, Nonunion, Open fractures

Abstract

BackgroundThe aim of this study was to evaluate the indications and incorporation of cryopreserved allograft in long bone fractures and nonunions.MethodsRetrospective study of 20 patients treated between 2005 and 2011, with 7 fractures and 14 long bones nonunions in which cryopreserved allograft bone was used (one patient had bilateral femoral involvement), associated with autograft in 11 cases. Average age 45.2 years (range 19 to 74). Ten women and ten men. Bone defects were classified according to whether they were circumferential or not.ResultsBony union after using morcellized allograft was achieved in 14 cases, after an average of 8 months (range 4 to 18), among the remaining 7 cases union was achieved after revision surgery in 5 cases, another case did not achieve consolidation, and an amputation was performed in another patient.ConclusionsBone autograft remains the gold standard in bone defect reconstructions. Using new extraction systems for autografts, such as reamed irrigation/aspiration (RIA, Synthes) has made the use of allograft in fractures infrequent. In our patients with multiple surgeries, bone defects or severe psychiatric disorders, the use of isolated cryopreserved allograft or associated with bone autograft obtained good results (18 cases with consolidation), although 5 patients required revision surgeries.

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Author Biographies

Ignacio Alejandro Fernández Savoy, Sanatorio Allende
Ortopedia y Traumatología
Leandro Salcedo Zunino, Sanatorio Allende
Ortopedia y Traumatología
Alejandro Malvarez, Sanatorio Allende
Ortopedia y Traumatología
Ignacio Pioli, Sanatorio Allende
Ortopedia y Traumatología
Bartolomé Luis Allende, Sanatorio Allende
Ortopedia y Traumatología
Christian Antonio Allende, Sanatorio Allende
Ortopedia y Traumatología

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Published
2015-06-11
How to Cite
Fernández Savoy, I. A., Salcedo Zunino, L., Malvarez, A., Pioli, I., Allende, B. L., & Allende, C. A. (2015). Outcomes of cryopreserved allograft in long bones fractures and nonunions. Revista De La Asociación Argentina De Ortopedia Y Traumatología, 80(2), 85-93. https://doi.org/10.15417/320
Section
Clinical Research

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