Synovial Sarcoma of the Knee: Case Report
Abstract
We present the case of a 22-year-old patient with chronic medial pain in the left knee, initially interpreted as a meniscal syndrome, who was later diagnosed with intra-articular synovial sarcoma (SS) after undergoing various diagnostic studies. Magnetic resonance imaging (MRI) at the time of consultation revealed a well-circumscribed, homogeneous mass with nonspecific characteristics in the medial compartment of the knee. Subsequent histological examination confirmed that the lesion was a synovial sarcoma originating from the synovial membrane. After review by a multidisciplinary team, wide resection of the lesion was performed,followed by ligament and capsular reconstruction. Synovial sarcoma is a rare mesenchymal tumor, accounting for less than 10% of soft tissue sarcomas. Its nonspecific MRI characteristics, along with ambiguous symptoms, make early diagnosis challenging. This condition should be considered in the differential diagnosis of nonspecific joint pain, especially when imaging findings do not align with more common pathologies.Downloads
References
Weiss SW, Goldblum JR. Enzinger and Weiss’s soft tissue tumors. 5th ed. Philadelphia PA: Mosby-Elsevier; 2008.
Friedman MV, Kyriakos M, Matava MJ, McDonald DJ, Jennings JW, Wessell DE. Intra-articular synovial sarcoma.
Skeletal Radiol 2013;42(6):859-67. https://doi.org/10.1007/s00256-013-1589-4
Hellwinkel JE, Farmer RP, Heare A, Smith J, Donaldson N, Fadell M, et al. Primary intra-articular synovial sarcoma of the knee: a report of two cases and review of the literature. Int J Radiol Imaging Technol 2018;4(1):1.
https://doi.org/10.23937/2572-3235.1510031
Al-Mohrej OA, Al-Jarallah SA, Al-Dakhil Allah HH, Pant R, Al-Zayed ZS. Synovial sarcoma presenting as an
intraarticular mass in a pediatric patient: a case report. BMC Musculoskelet Disord 2020;21(1):283.
https://doi.org/10.1186/s12891-020-03312-3
Caravias P. Sarcoma sinovial de rodilla. Rev Asoc Argent Ortop Traumatol 1996;60(2):79-83. Disponible en:
https://www.aaot.org.ar/revista/1993_2002/1996/1996_1/610112.pdf
Bateman JE. Gallie technique for repair of recurrent dislocation of the shoulder. Surg Clin North Am 1963;43:1655-62. https://doi.org710.1016/s0039-6109(16)37157-2
Murphey MD, Gibson MS, Jennings BT, Crespo-Rodríguez AM, Fanburg-Smith J, Gajewski DA. Imaging of
synovial sarcoma with radiologic-pathologic correlation. Radiographics 2006;26:1543-65. https://doi.org/10.1148/rg.265065084
Ferrari A, Chi YY, De Salvo GL, Orbach D, Brennan B, Randall RL, et al. Surgery alone is sufficient therapy for
children and adolescents with low-risk synovial sarcoma: a joint analysis from the european paediatric soft tissue
sarcoma study group and the children’s oncology group. Eur J Cancer 2017;78:1-6. https://doi.org/10.1016/j.ejca.2017.03.003
Kransdorf MJ. Malignant soft-tissue tumors in a large referral population: distribution of diagnoses by age, sex, and location. Am J Roentgenol 1995;164:129-34. https://doi.org/10.2214/ajr.164.1.7998525
Weiss SW, Goldblum JR, Folpe AL. Malignant soft tissue tumors of uncertain type. En: Enzinger & Weiss’s soft
tissue tumors. 5th ed. Philadelphia PA: Mosby-Elsevier; 2008.
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