Non-surgical management of osteopetrosis: two case reports an review of the literature
Abstract
Osteopetrosis (also known as Albers-Schönberg disease) is a syndrome that includes four classic types and is characterized by bone dysplasia and lack of bone resorption due to abnormal osteoclastic activity and consequent development of brittle and hard bone that is prone to fractures that are difficult to treat surgically. Herein we present two cases of osteopetrosis with diaphyseal fractures of the humerus, both managed with non-surgical treatment. The objectives of our manuscript are to document our experience in the management of these cases and review the literature. The non-invasive treatment provides the best outcome for dyaphyseal fractures on the humerus in patients with osteopetrosis, given that the quality of the bone in these patients impairs the implementation of osteosynthesis. In addition, the placement of implants can lead to complications such as infections, delayed consolidation and pseudoarthrosis, among others. Surgical treatment should reserved for certain patients such as those with delayed consolidation, pseudoarthrosis, a history of repeated fractures, pre-existing deformity and those who are at risk for the development of disabling deformities or do not respond to non-surgical treatmentDownloads
References
Granados Sandoval E, Martínez Estrada JG, Zepeda Cianca R, Trejo Pimentel A, Sandoval González C, Barrón JC. Osteopetrosis (enfermedad de Albers-Schonberg): reporte de un caso y revisión clínica. Med Int Mex 2007;23(6):542-5.
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Landa J, Di Cesare N. Orthopaedic management of the patient with osteopetrosis. J Am Acad Orthop Surg 2007;15:654-62. https://doi.org/10.5435/00124635-200711000-00004
Bhargava A, Vagela M, Lennox CME. Challenges in the management of fractures in osteopetrosis. Review of literature and technical tips learned from long-term management of seven patients. Injury 2009;40:1167-71. https://doi.org/10.1016/j.injury.2009.02.009
Rafiq I, Kapoor1 A, Burton DJC, Haines JF. A new modality of treatment for non-united fracture of the humerus in a patient with osteopetrosis: a case report. J Med Case Reports 2009;3:15. https://doi.org/10.1186/1752-1947-3-15
Armstrong DG, Newfield JT, Gillespie R. Orthopedic management of osteopetrosis: results of a survey and review of the literature. J Pediatr Orthop 1999;19(1):122-32. PMID: 9890301
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